Saturday, January 8, 2011
Initial findings from a yet-to-be publshed study
A recent study was done to assess the pathological state in various CFS patients, healthy patients, and a handful of patients given the drugs Viread and Isentress for 3 months. All CFS patients demonstrated elevated titres of at least one of: Varicella Zoster Virus, EBV, CMV, HHV-6, and HHV-7, and one patient with HHV-8 (Kaposi's Sarcoma Associated Virus). Either or both of Mycoplasma Incognitans or Chlamydia Pneumoniae was found with alarming prevalence in CFS patients, yet was found in remarkably low prevalence in healthy individuals. In the small sample, viral titers began to fall 2 and 3 weeks after commencement of two antiretrovirals, and rapid declines in Mycoplasma Incognitans and Chlamydia pneumoniae occured after 1 month. It is of note that Mycoplasma Incognitans was once suspected of being behind the pathogenesis of CFS, and it turned out to be a false lead. Although more subtle than in HIV patients (CMV retinitis is found in HIV patients), a pattern of immune dysfunction is seen in both CFS and HIV. More news on January 17th.